Making therapeutic sense of antisense oligonucleotides
Making therapeutic sense of antisense oligonucleotides
newsdepo.com
Researchers have devised a molecular structural modification that boosts the efficacy of antisense oligonucleotide-based drugs by replacing the RNA strand of a heteroduplex oligonucleotide with DNA. This advance expands the scope and clinical applicability o
Viewing upper gastrointestinal cancers in a new light
Viewing upper gastrointestinal cancers in a new light
newsdepo.com
Researchers report the use of Linked Color Imaging, an innovative modality that specifically combines selected wavelengths of light for illumination in upper gastrointestinal endoscopy. This method, by enhancing the subtle variations in red and white hues tha
Neither liquid nor solid
Neither liquid nor solid
newsdepo.com
Discovery of liquid glass sheds light on the old scientific problem of the glass transition: An interdisciplinary team of researchers has uncovered a new state of matter, liquid glass, with previously unknown structural elements - new insights into the natur
Using solar energy and agriculture to limit climate change, assist rural communities
Using solar energy and agriculture to limit climate change, assist rural communities
newsdepo.com
Co-developing land for both solar photovoltaic power and agriculture could provide 20% of total electricity generation in the United States with an investment of less than 1% of the annual US budget, new researchers found.
Uncovering how grasslands changed our climate
Uncovering how grasslands changed our climate
newsdepo.com
Grasslands are managed worldwide to support livestock production, while remaining natural or semi-natural ones provide critical services that contribute to the wellbeing of both people and the planet. Human activities are however causing grasslands to become
How plants adapt their root growth to changes of nutrients
How plants adapt their root growth to changes of nutrients
newsdepo.com
Nitrogen is one the most essential nutrients for plants. Its availability in the soil plays a major role in plant growth and development, thereby affecting agricultural productivity. Scientists were now able to show, how plants adjust their root growth to var
3D-printed smart gel changes shape when exposed to light
3D-printed smart gel changes shape when exposed to light
newsdepo.com
Inspired by the color-changing skin of cuttlefish, octopuses and squids, engineers have created a 3D-printed smart gel that changes shape when exposed to light, becomes 'artificial muscle' and may lead to new military camouflage, soft robotics and flexible di
Eurasian eagle owl diet reveals new records of threatened big-bellied glandular bush-crickets
Eurasian eagle owl diet reveals new records of threatened big-bellied glandular bush-crickets
newsdepo.com
Bird diets provide a real treasure for research into the distribution and conservation of their prey, conclude scientists after studying the Eurasian Eagle Owl in southeastern Bulgaria.
Uncovering how plants see blue light
Uncovering how plants see blue light
newsdepo.com
Plants can perceive and react to light across a wide spectrum. New research shows how plants can respond to blue light in particular by revealing the structure of cryptochrome-2, the molecule that reacts to blue light.
Scientists develop new approach to understanding massive volcanic eruptions
Scientists develop new approach to understanding massive volcanic eruptions
newsdepo.com
An international volcanology team has created a first-of-its kind tool that can aid scientists in understanding past explosive eruptions that shaped the earth and improve the way of estimating hazards of future eruptions.
Reawakened geyser does not foretell Yellowstone volcanic eruptions
Reawakened geyser does not foretell Yellowstone volcanic eruptions
newsdepo.com
Geyser eruptions, like volcanic eruptions, are a mystery, so the reactivation of Steamboat Geyser in Yellowstone in 2018 provided an opportunity to explore why geysers turn off and on, and what determines their periodicity. Researchers found little evidence o
New tool for reconstructing ancient sea ice to study climate change
New tool for reconstructing ancient sea ice to study climate change
newsdepo.com
A previously problematic molecule turns out to be a reliable proxy for reconstructing sea ice, a new study by Brown University researchers shows.
Antibiotic-resistant bacteria: Fluoride to the rescue?
Antibiotic-resistant bacteria: Fluoride to the rescue?
newsdepo.com
Scientists have long been aware of the dangerous overuse of antibiotics and the increasing number of antibiotic-resistant microbes that have resulted. While over-prescription of antibiotics for medicinal use has unsettling implications for human health, so to
Focusing on diversion yields positive results for kids with behavioral issues
Focusing on diversion yields positive results for kids with behavioral issues
newsdepo.com
Researchers found that focusing on diversion -- instead of detention -- yields positive results for youth with behavioral health issues.
Scientists discover how mother-of-pearl self-assembles into a perfect structure
Scientists discover how mother-of-pearl self-assembles into a perfect structure
newsdepo.com
Researchers describe, how structural defects in self-assembling nacre attract and cancel each other out, eventually leading to a perfect periodic structure.
Single-cell analysis of metastatic gastric cancer finds diverse tumor cell populations associated with patient outcomes
Single-cell analysis of metastatic gastric cancer finds diverse tumor cell populations associated with patient outcomes
newsdepo.com
Researchers who profiled more than 45,000 individual cells from patients with peritoneal carcinomatosis (PC), a specific form of metastatic gastric cancer, defined the extensive cellular heterogeneity and identified two distinct subtypes correlated with patie
Pandas' popularity not protecting neighbors
Pandas' popularity not protecting neighbors
newsdepo.com
Doubt is cast on the long-held hope that the conservation protections granted pandas and other adored threatened species extended to their wildlife neighbors, calling for broader conservation efforts.
Supercapacitors challenge batteries
Supercapacitors challenge batteries
newsdepo.com
A team has developed a highly efficient supercapacitor. The basis of the energy storage device is a novel, powerful and also sustainable graphene hybrid material that has comparable performance data to currently utilized batteries.
First glimpse of polarons forming in a promising next-gen energy material
First glimpse of polarons forming in a promising next-gen energy material
newsdepo.com
Polarons affect a material's behavior, and may even be the reason that solar cells made with lead hybrid perovskites achieve extraordinarily high efficiencies in the lab. Now scientists have used an X-ray free-electron laser to directly see and measure the fo
Astronomers agree: Universe is nearly 14 billion years old
Astronomers agree: Universe is nearly 14 billion years old
newsdepo.com
From an observatory high above Chile's Atacama Desert, astronomers have taken a new look at the oldest light in the universe. Their observations, plus a bit of cosmic geometry, suggest that the universe is 13.77 billion years old - give or take 40 million yea
Prediabetes subtypes identified
Prediabetes subtypes identified
newsdepo.com
All prediabetes is not the same: in people in the preliminary stages of type 2 diabetes, there are six clearly distinguishable subtypes, which differ in the development of the disease, diabetes risk, and the development of secondary diseases. The new classifi
Better together: Scientists discover applications of nanoparticles with multiple elements
Better together: Scientists discover applications of nanoparticles with multiple elements
newsdepo.com
As catalysts for fuel cells, batteries and processes for carbon dioxide reduction, alloy nanoparticles that are made up of five or more elements are shown to be more stable and durable than single-element nanoparticles.
Research shows a few beneficial organisms could play key role in treating type 2 diabetes
Research shows a few beneficial organisms could play key role in treating type 2 diabetes
newsdepo.com
Researchers have found that a few organisms in the gut microbiome play a key role in type 2 diabetes, opening the door to possible probiotic treatments for a serious metabolic disease affecting roughly one in 10 Americans.
A high order for a low dimension
A high order for a low dimension
newsdepo.com
Spintronics refers to a suite of physical systems which may one day replace many electronic systems. To realize this generational leap, material components that confine electrons in one dimension are highly sought after. For the first time, researchers create
New data-driven global climate model provides projections for urban environments
New data-driven global climate model provides projections for urban environments
newsdepo.com
Cities only occupy about 3% of the Earth's total land surface, but they bear the burden of the human-perceived effects of global climate change, researchers said. Global climate models are set up for big-picture analysis, leaving urban areas poorly represente
Inflammation from ADT may cause fatigue in prostate cancer patients
Inflammation from ADT may cause fatigue in prostate cancer patients
newsdepo.com
Researchers are investigating whether inflammation in the body, a side effect of ADT, contributes to these symptoms in prostate cancer patients. They pinpoint a specific inflammation marker that is associated with increased fatigue in this group of patients.
Risk of extinction cascades from freshwater mussels to a bitterling fish
Risk of extinction cascades from freshwater mussels to a bitterling fish
newsdepo.com
Reproduction of native and invasive bitterling fishes and their hybridisation was studied in Japan. We collected mussels in which these bitterlings lay their eggs, kept them in aquaria, collected eggs/larvae ejected from mussels, and genotyped them. We found
Long live the efficient, pure-blue OLED
Long live the efficient, pure-blue OLED
newsdepo.com
In work that could help to solve the challenge of finding blue light sources matching the performance of red and green ones for displays using organic light-emitting diodes, researchers have demonstrated devices that produce pure-blue emission with high effic
Why patients with cancer spread to the liver have worse outcomes
Why patients with cancer spread to the liver have worse outcomes
newsdepo.com
A new study finds that tumors in the liver siphon off critical immune cells, rendering immunotherapy ineffective. But coupling immunotherapy with radiotherapy to the liver in mice restored the immune cell function and led to better outcomes.
Using artificial intelligence to find new uses for existing medications
Using artificial intelligence to find new uses for existing medications
newsdepo.com
Scientists have developed a machine-learning method that crunches massive amounts of data to help determine which existing medications could improve outcomes in diseases for which they are not prescribed.
Alert system shows potential for reducing deforestation, mitigating climate change
Alert system shows potential for reducing deforestation, mitigating climate change
newsdepo.com
Forest loss declined 18% in African nations where a new satellite-based program provides free alerts when it detects deforestation activities.
Oregon's Medicaid expansion improved prenatal care access, birth outcomes
Oregon's Medicaid expansion improved prenatal care access, birth outcomes
newsdepo.com
A pair of recent studies found that Oregon's Medicaid expansion in 2014 has led to increased prenatal care among low-income women, as well as improved health outcomes for newborn babies.
Pollutants rapidly changing the waters near Ieodo Island
Pollutants rapidly changing the waters near Ieodo Island
newsdepo.com
A research team identifies the cause of ocean fertilization in northeast Asian waters.
Frequent travel could make you 7% happier
Frequent travel could make you 7% happier
newsdepo.com
People dreaming of travel post-COVID-19 now have some scientific data to support their wanderlust. A new study shows frequent travelers are happier with their lives than people who don't travel at all.
Drug discovery study identifies promising new compound to open constricted airways
Drug discovery study identifies promising new compound to open constricted airways
newsdepo.com
In a preclinical study, researchers identified and characterized 18 new compounds (agonists) that activate bitter taste receptor subtype TAS2R5 to promote relaxation of human airway smooth muscle cells. The cross-disciplinary team found 1,10 phenanthroline-5,
How to identify heat-stressed corals
How to identify heat-stressed corals
newsdepo.com
Researchers have found a novel way to identify heat-stressed corals, which could help scientists pinpoint the coral species that need protection from warming ocean waters linked to climate change, according to a new study.
Comb of a lifetime: a new method for fluorescence microscopy
Comb of a lifetime: a new method for fluorescence microscopy
newsdepo.com
Conventional fluorescence microscopy provides poor quantitative information of the sample because it only captures fluorescence intensity, which changes frequently and depends on external factors. Now, scientists have developed a new fluorescence microscopy t
Putty-like composites of gallium metal with potential for real-world application
Putty-like composites of gallium metal with potential for real-world application
newsdepo.com
Researchers created a novel functional composite of gallium with putty or paste-like physical properties. The composite possesses excellent electromagnetic shielding properties as well as thermal conductivity.
See live cells with seven times greater sensitivity using new microscopy technique
See live cells with seven times greater sensitivity using new microscopy technique
newsdepo.com
Experts in optical physics have developed a new way to see inside living cells in greater detail using existing microscopy technology and without needing to add stains or fluorescent dyes.
New virtual screening strategy identifies existing drug that inhibits COVID-19 virus
New virtual screening strategy identifies existing drug that inhibits COVID-19 virus
newsdepo.com
A novel computational drug screening strategy combined with lab experiments suggest that pralatrexate, a chemotherapy medication originally developed to treat lymphoma, could potentially be repurposed to treat COVID-19.
